The research direction of Brain Circulation reflects a comprehensive focus on cerebrovascular disease and its treatment, particularly in the area of stroke and brain injury. The journal is dedicated to publishing innovative research that not only advances the understanding of the pathophysiological mechanisms of cerebrovascular disease, but also facilitates the development and application of new therapeutic strategies.

The journal especially emphasizes the importance of cerebral blood flow reperfusion, because reperfusion is a key step in stroke treatment and can significantly affect the prognosis of patients. Researchers' work in this area includes not only the search for more effective reperfusion techniques, but also the prevention and management of complications that may arise during reperfusion. Attention is also being paid to non-pharmacological approaches, such as oxygen therapy, hypothermia, and remote ischemic adaptation, which have shown potential efficacy in the treatment of stroke. Research into these treatments could help provide patients with more diverse treatment options, especially in cases where traditional medications have limited effectiveness.